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A Smoked Brisket Grilled Cheese sandwich cut in half and stacked, showing melted cheese and tender brisket.
Maryam

Smoked Brisket Grilled Cheese

Leftover brisket gets the ultimate upgrade with melty cheese, caramelized onions, and crispy buttered bread.
Prep Time 10 minutes
Cook Time 15 minutes
Total Time 25 minutes
Servings: 2 sandwiches
Course: Dinner, lunch
Cuisine: American, Barbecue
Calories: 720

Ingredients
  

For the Sandwiches
  • 4 slices sourdough bread thick-cut, about 3/4 inch
  • 8 oz smoked brisket warmed, chopped into bite-sized pieces
  • 4 oz sharp cheddar cheese shredded, not pre-shredded
  • 3 tbsp unsalted butter softened, divided
  • 1 small yellow onion thinly sliced
  • 1 tsp pickle juice from dill pickles, optional but recommended
  • 1 tbsp Dijon mustard

Equipment

  • Large Skillet or Griddle
  • Small Skillet

Method
 

Prep
  1. Melt 1 tablespoon butter in a small skillet over medium-low heat. Add sliced onion and cook slowly, stirring occasionally, until deep golden and jammy, about 12 minutes. If they threaten to burn, add a splash of water. Set aside.
  2. While onions cook, gently warm chopped brisket in a covered dish in the microwave or a low oven until just heated through, about 2 minutes. You want it warm, not hot enough to steam the bread later.
Assemble
  1. Spread Dijon on one side of each bread slice. Divide half the cheddar between two slices, top with warmed brisket, caramelized onions, and remaining cheddar. Cap with remaining bread, mustard side down. Spread remaining 2 tablespoons butter on the outside of both sandwiches.
Cook
  1. Heat a large skillet over medium-low heat. Cook sandwiches until bread is deeply golden and cheese is fully melted, about 4-5 minutes per side. Press gently with a spatula for even contact. If cheese is slow to melt, cover briefly with a lid.
  2. Transfer to a cutting board, let rest 1 minute so the cheese sets slightly, then slice diagonally. Serve with pickle juice on the side for dipping, or drizzle a few drops over the cut sandwich for brightness.

Notes

Cold brisket straight from the fridge will cool your cheese and prevent proper melting - always warm it first. If your brisket is heavily sauced, blot excess with paper towels to avoid soggy bread. For extra crunch, use mayonnaise instead of butter on the outside of the bread.